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Acellular Dermal Matrices Market Definitely Accelerating In the industry

Acellular dermal matrix is a biologically derived product, which is devoid of cells. The main components of acellular dermal matrix include collagen and elastic fibers. It has applications in plastic surgery, general surgery, breast reconstruction, cosmetic surgery, wound healing, and others. The matrix is derived from different sources such as human, porcine, bovine, and others.

Global Acellular Dermal Matrices Market – Impact of the Coronavirus (COVID-19) Pandemic

COVID-19 pandemic is expected to decrease the growth of the global acellular dermal matrices market over the forecast period. For instance, according to the World Heart Federation, 2020, older people over the age of 60 years and people suffering from underlying medical conditions such as cardiovascular disease, hypertension, diabetes, chronic respiratory disease, and cancer are more prone to the coronavirus infection compared to younger population. Furthermore, according to World Health Organization (WHO), on April 2, 2020, it was reported that in Europe, 95% of the coronavirus infection was recorded in the population older than 60 years, while over 50% of the infection were recorded in the population of the age group of 80 years and more.

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According to the Breast Cancer Now, research and care organization: 18th September 2020, around 1,500 breast cancer patients, breast reconstructive surgery got delayed due to COVID-19 pandemic. According to the same source, in the U.K., around 55,000 women and 370 men are diagnosed with breast cancer per year. Moreover, in UK, 14,850 of the 55,000 women undergo breast mastectomy each year. Such delay in the breast reconstruction surgeries may affect the self-esteem, body image and sexuality in patients, which is expected to hamper the market growth over the forecast period.

The global acellular dermal matrices market is estimated to be valued at US$ 6,483.6 Mn in 2020 and is expected to exhibit a CAGR of 15.1% over the forecast period (2020-2027).

Increasing product launches by the market players is expected to drive growth of the global acellular dermal matrices market over the forecast period.

Market players are involved in launching new products in different regions, which is expected to increase the customer base, thereby driving growth of the global acellular dermal matrices market over the forecast period. For instance, in 2019, LifeNet Health, Inc., launched first human acellular dermal matrices, Dermacell AWM. The matrix is indicated for wound treatment such as diabetes foot ulcer.

Increasing inorganic activities such as acquisitions is expected to fuel growth of the global acellular dermal matrices market.

Market players are involved in organic activities such as acquisitions, which is expected to drive acellular dermal matrices market growth over the forecast period. For instance, in 2017, Allergan Inc., acquired LifeCell Corporation, a regenerative medicine company. Allergan Inc., is focused on offering acellular dermal matrices products for the plastic surgeons, by combining the innovative medical aesthetics and plastic surgery portfolio of Allergan Inc., and LifeCell Corporation.

Rising number of plastic surgeries worldwide is expected to drive growth of the global acellular dermal matrices market over the forecast period. For instance, according to the American Society of Plastic Surgeons: 2019, globally, the total number of cosmetic procedures carried out in 2019 and 2018 were 18,160,785 and 17,902,692, respectively. Out of which the minimally invasive cosmetic procedures carried out in 2019 and 2018 were 16,349,031 and 16,090,952 respectively. The cosmetic procedures involving the acellular dermal matrix carried out in 2019 and 2018 were, 9,117 and 8,575.

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Global Acellular Dermal Matrices Market – Regional Analysis

On the basis of region, the global acellular dermal matrices market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.

North America is expected to dominate the global acellular dermal matrices market, owing to the increasing awareness of breast cancer and increasing number of plastic surgeries in the region. For instance, in November 2018, breast reconstruction awareness program was conducted in the Windsor Regional Hospital, Canada, with the special purpose to help and educate local women about breast cancer and breast reconstruction. Moreover, according to the International Society of Aesthetic Plastic Surgery: in 2019, highest number of plastic surgery procedures were carried out in the U.S., i.e., 18.7%.

Furthermore, Asia Pacific is also estimated to witness significant growth in the acellular dermal matrices market, owing to increasing government initiatives about breast cancer treatment. For instance, in February 2018, the state health department of Tamil Nadu, India launched free cosmetic surgery clinic at the Government Stanley Medical College and Hospital, which offers free breast reconstruction surgery, as well as breast augmentation and breast reduction surgeries for people below the poverty line.

Global Acellular Dermal Matrices Market – Competitive Landscape

Major players operating in the global acellular dermal matrices market include Zimmer Biomet, Stryker Corporation, Staumann, Allergan, Inc., Conmed, Integra LifeSciences Corporation, Aziyo Biologics, Hospital Innovations, Medtronic, Inc., Synthes, Inc., Gunze Corp., Cook Medical Incorporated, C. R. Bard, Inc., and HANS BIOMED CORP.

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Global Nanoparticles Market Analysis And Growth

Particles between 1 and 100 nanometers (nm) in size known as nanoparticles. An individual nanoparticle molecule behaves as a complete unit in terms of its property and transportation. Rapidly increasing public awareness for nanotechnology and introduction of new technologies will have many beneficial consequences. Moreover, increasing applications of nanotechnology in drug development and stringent guidelines for developing improved medical products are some of the prime factors which is expected to witness significant growth over the forecasted period. Furthermore, huge capital investment and high cost of nanoparticle analysis instrument is one of the key restraint for the growth of nanoparticle market. Due to its wide applications in healthcare, biomedical, electronics and among others the nanoparticle is currently a new area of research among many scientist. Rising government spending on pharmaceuticals and bio technology research and development and increasing focus on nanotechnology research also expected to experience significant growth. North America dominated the global nanoparticles market due to increasing chronic diseases such as diabetes, cardiovascular and cancer. Moreover, Europe is expected to witness the highest growth during the forecasted period, due to rapid research and development for nanoparticles. However, due to rampant economic growth of China and India, Asia Pacific is also expected to witness decent growth during the forecasted period. Furthermore, India is also an emerging hub for pharmaceuticals research and development.

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Nanoparticles Market Taxonomy

On the basis of technology, the global market is classified into:

  • Liposomes
  • Nanotubes
  • Polymeric nanoparticles
  • Polymer conjugated drugs
  • Dendrimers
  • Inorganic nanoparticles
  • Others

On the basis of end user, the global market is classified into:

  • Pharmaceuticals industry
  • Biochemical industry
  • Research institutions
  • others

Nanoparticles Market Outlook – Surge in Drug Development in Pharmaceuticals Industry Augmenting Market Growth

Expansion of medical diagnostic industry and wide application of nanotechnology in healthcare sector such as neurology, cardiology and anti-infective is estimated to have a decent growth for nanoparticles market in the forecast period. Depending upon preparation methods nanoparticles, nanocapsules or nanospheres can be obtained. A long circulating particle made up of Biodegradable polymeric nanoparticles with hydrophilic polymer coating of poly ethylene glycol (PEG), used as a powerful drug delivery device. Due to its ability to deliver peptides, proteins and genes, it is also used as a DNA carrier in gene therapy. Numerous advantages for nanoparticles in drug delivery system is expected to Spector enormous growth during the forecasted period. Moreover, growing public awareness, improved technology and increase in chronic diseases escalate the global nanoparticles industry in North America. Emerging economy of Asia Pacific, such as China and India is expected to witness significant growth over the forecasted period.

Nanoparticles Market Challenges – Huge Capital Investment needed in Research and Development

Huge capital investment for research and development of new product and technology. Moreover, high cost of nanoparticles analysis instruments is expected to be one of the key restraints for global nanoparticles market.

Nanoparticles Market – Regulatory Scenario:

  • August, 2015, U.S. Food and Drug Administration (FDA), issued guidance to address various issues related to the use of nanotechnology in food ingredients intended for use in food for animals.
  • June, 2014, U.S. Food and Drug Administration (FDA), issued three guidelines related to the use of nanotechnology in regulated products, including cosmetics and food substances.

Some of the key players in the market includes Abraxis Biosciences, Inc., Novartis International AG, Gilead Sciences, Inc., Johnson & Johnson, Sigma-Tau Pharmaceuticals, Inc. Amgen, Inc., and Nano Interface Technology, Inc., Malvern Instruments Ltd., Horiba Ltd., Beckman Coulter, Shimadzu Corporation, Agilent Technology Inc., Hitachi Ltd., Wyatt Technology, among others.

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Key Developments

  1. Key companies in the market are focused on various business strategies such as merger and acquisition, in order to gain competitive edge in the market. For instance, in January 2019, Horiba Ltd., a manufacturer of precision instruments, announced that Horiba Instruments Incorporated acquired MANTA Instruments, Inc., which has high reputation for its nanoparticle characterization technology.

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Pipettes and Accessories Market Analysis And Growth 2020

Pipettes are used in biotechnology, pharmaceutical, and chemical laboratories in order to transfer certain volume of liquids. Micropipettes are important in molecular biology experiments, which require microliter amounts of solutions whereas serological pipettes are used in microbiology laboratories to prepare cell cultures that require media preparations of milliliter volumes. Volume transfers with sterile cultures and solutions using instruments such as micropipettes and serological pipettes are one of several types of routine techniques performed in a laboratory. Pipette designs such as electronic pipetting, ultralight pipettes, plungers positions in more user-friendly configurations, and reducing frictional forces help in reducing strain.

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The global pipettes and accessories market size was valued at US$ 1.3 billion in 2017 and is expected to witness a CAGR of 4.0% over the forecast period (2018 – 2026).

Increasing prevalence of chronic constipation is expected to drive the pipettes and accessories market growth

Increasing research and development in the field of pharmaceuticals and biotechnology due to high prevalence of infectious diseases and cancer are the major factors driving the pipettes and accessories market growth. According to 2012 European Union Industrial R&D Investment Scoreboard, the pharmaceutical and biotechnology sectors represented 17.7% of business R&D expenditure in the world.

Pharmaceutical companies are increasingly focusing on conducting research and development activities as well as outsourcing such activities to academic and private research institutes. This in turn is increasing demand for liquid handling systems such as pipettes. Pharmaceutical companies are also increasingly outsourcing their research activities to privately-owned Contract Research Organizations (CRO) to maintain their presence in the growing pharmaceutical and biotechnology market. For instance, in May 2018, Ritter Pharmaceuticals, Inc., a manufacturer of novel therapeutic products entered into an agreement with Medpace, a CRO to conduct the first of two pivotal Phase 3 clinical trials for RP-G28 among patients with lactose intolerance.

Pipettes and Accessories Market Restraints

Pipettes are extensively used for various applications and are thus exposed to various types of reagents and specimens. They can introduce quality-specific concerns regarding precision and accuracy and can also lead to safety risks, particularly while working with hazardous chemicals or specimens with a high infection risk. Furthermore, high cost of electronic pipettes can be a negative factor for the market growth. For instance, the cost of the Xplorer plus electronic single channel pipette with charging adapter is around US$ 1000. This product may not be affordable for several laboratories due to its high price. However, manual pipettes tend to be more economical, though they produce greater variability, particularly for highly sensitive or expensive pipetting applications.

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Pipettes and Accessories Market – Regional Insights

On the basis of region, the global pipettes and accessories market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is the largest market for biotechnology and pharmaceutical research and manufacturing and therefore, demand for pipettes and accessories is the highest in the region. According to a study published by the International Trade Administration in 2016, the U.S. is the major hub for drug manufacturing and is expected to grow considerably in future.

Asia Pacific pipettes and accessories market is expected to witness significant growth over the forecast period. This is owing to increasing clinical trials from biopharmaceutical industry in the region due to easy patient recruitment and availability of skilled professionals to conduct research experiments. This in turn leads to increasing number of research laboratories being set up in the region, thereby propelling demand for pipettes and accessories. For instance, in March 2017, Herbalife Company associated with Syngene established a new research and development lab at Bangalore, India.

According to the India Brand Equity Foundation June 2018 report, Government of India has reduced the approval time for new facilities to propel investments for drug manufacturers under the ‘Pharma Vision 2020’. Such initiatives are expected to attract foreign investors for the development of new manufacturing units, in turn increasing demand for pipettes and accessories during the forecast period.

Pipettes and Accessories Market – Competitive Landscape

Key players operating in the global pipettes and accessories market include, Thermo Fisher Scientific, Eppendorf AG, Hamilton Company, Mettler-Toledo International, Inc., Lab Depot Inc., Sartorius AG, BRAND GmbH + CO KG, Capp ApS, Corning Inc., Denville Scientific, Inc., Gilson, Inc., Greiner Bio-One International GmbH, Integra Biosciences AG, Kimble-chase, Nichiryo Co., Ltd., and Socorex ISBA SA.

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Human Microbiome Market Analysis, Growth, Share And Upcoming Trends By 2027

Human microbiome play a major role in modern healthcare, as it allows easy digestion of food, regulation of immune system, and production of vitamins such as Vitamin K, Vitamin B, and Vitamin B12, which is essential for blood coagulation.

The global human microbiome market size was valued at US$ 46,913.4 million in 2017, and is expected to exhibit a CAGR of 17.5% over the forecast period (2018 – 2026).

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Increasing prevalence of gastrointestinal disorder and cancer is expected to propel growth of the human microbiome market

Human microbiome boosts immunity, nutrition, and other uses. High incidence of C. difficile infection is expected to propel demand for antibiotics, prebiotics, and probiotics, which in turn is expected to drive the market growth. According to the Centers for Disease Control and Prevention in 2015, Clostridium difficile infection (CDI) is one of the most common healthcare-associated infections in the U.S., affecting over 500,000 people and causing about 29,000 deaths each year. According to a study published in the Clinical Infectious Disease Journal in 2015, about 25% to 33% of antibiotic-associated diarrhea and 90% of pseudomembranous enteritis are caused by CDI.

Similarly, according to International Agency for Research on Cancer September 2018 estimates, around 9.6 million death and 18.1 million new cases of cancer will be diagnosed in 2018.

Furthermore, introduction of probiotic may induce change in intestinal microbiota and can stabilize microbial communities, which may prevent gut inflammation, propelling growth of the human microbiome market during the forecast period. For instance, in February 2018, Dannon expanded its Activia range with the introduction of a range of low-fat yogurt drinks, Activia Dailies, in the U.S. Activia Dailies contain live and active probiotics.

Microbiome based diagnostic and therapeutic is relatively new concept which creates concern about its safety profile. Moreover, there is concern about true efficacy of microbiome-based platform. The establishment of link between dysbiosis of microbiome and disease is critical to establish clinical potential. For a microbiome-based diagnostic, establishing clinical evidence of the link between biomarkers and disease (cancer biomarkers) would be significant. This scenario presents unique set of a challenge for designing clinical trials as the lack of uniformity in microbiome in target patient pool may affect clinical trial outcomes and reproducibility.

Increasing prevalence of obesity in Asia Pacific is expected to boost the market growth

Asia Pacific holds dominant position in the global human microbiome market, owing to high prevalence of obesity shows alterations in gastrointestinal microbiota. According to Asian Development Bank Institute (ADBInstitute), June 2017 estimates around 1 billion people in Asia and the Pacific were obese and around 40.9% of adults in the region were overweight in 2013, compared with 34.6% in 1990. Increasing focus on human microbiome therapy in treatment of cancer in the region is also expected to boost the market growth. According to Asian Pacific Journal of Cancer Prevention, February 2004, in year 2000, around 3 million new cancer cases, and around 2 million cancer deaths, and around 5.4 million people living with cancer in Asia Pacific region.

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Moreover, increase in need of early detection and diagnostics of cancer is expected to boost demand for human microbiome market. For instance, in August 2014, National Center for Biotechnology Information (NCBI), stated that Colorectal Cancer (CRC) is third most commonly diagnosed malignancy globally which accounts for around half million deaths annually. The abnormality in gut microbiome in CRC, if diagnosed early can exceed survival rate around 90%.

Key Players

Major players operating in the global human microbiome market include, Enterome Bioscience, Yakult Honsha Co., Ltd., DuPont, Metabiomics Corporation, ViThera Pharmaceuticals, Second Genome Inc., AOBiome LLC, Seres Therapeutics, uBiome, Inc., Rebiotix, Inc., Synthetic Biologics, Inc., MicroBiome Therapeutics LLC, Vedanta BioSciences, Osel, Inc., and Merck & Co., Inc.

About Coherent Market Insights

Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

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Coherent Market Insights

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Phone: US +12067016702 / UK +4402081334027

Email: sales@coherentmarketinsights.com